Which class of stimulants are often abused for the euphoric rush that high doses can produce?

Amphetamines are a class of stimulants that are often abused due to the euphoric rush and increased energy levels they can produce at high doses. This effect is primarily the result of their ability to increase the levels of neurotransmitters, such as dopamine and norepinephrine, in the brain, leading to heightened mood and alertness. Users may seek out this euphoric high, which can contribute to the potential for abuse and addiction.

While other substances listed may have psychological or physical effects, they do not primarily fit the description of stimulants producing a euphoric rush in the same way that amphetamines do. Understanding the distinct nature of amphetamines and their appeal in recreational use highlights why this class of drugs is particularly noted for the euphoric rush associated with high doses.